Tibolone and Breast Cancer
- Author:
Jae Kyung LEE
1
;
Hyewon YUN
;
Heeyon KIM
;
Bo Hyon YUN
;
Seok Kyo SEO
Author Information
- Publication Type:REVIEW ARTICLE
- From:Journal of Menopausal Medicine 2023;29(3):92-96
- CountryRepublic of Korea
- Language:English
- Abstract: Tibolone, a selective tissue estrogenic activity regulator, is a synthetic steroid with distinct pharmacological and clinical characteristics in contrast to conventional menopausal hormone therapy. Tibolone induces estrogenic activity in the brain, vagina, and bone but remains inactive in the endometrium and breast. In particular, several studies have investigated whether tibolone usage increases the risk of breast cancer. This study aims to determine the effects of tibolone on the breast by focusing on the relation between tibolone use and breast cancer. Our investigation emphasizes recent studies, particularly those based on Asian populations.
