Clinical and Laboratory Characteristics of Kawasaki Disease and COVID-19-Related Multisystem Inflammatory Syndrome in Children
10.3346/jkms.2023.38.e410
- Author:
Duc Long PHI
1
;
Thi Loi DAO
;
Minh MANH TO
;
Thanh Binh NGUYEN
;
Duy Cuong NGUYEN
;
Philippe GAUTRET
;
Van Thuan HOANG
Author Information
1. Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam
- Publication Type:Brief Communication
- From:Journal of Korean Medical Science
2023;38(49):e410-
- CountryRepublic of Korea
- Language:English
-
Abstract:
Geographical and racial factors constitute important distinctions between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C), but no study has been conducted in Vietnam. Forty-one children with KD from January 2018 to July 2020 and 42 with KD/MIS-C from August 2020 to December 2022 were included in this study. Of the patients, 52.3% were aged between 12 and 35 months. Only two were aged over 5 years, and both were belong to the KD/MIS-C group. A 59.5% of the patients were male. Apart from fever, all symptoms tended to be more frequent in patients with KD/MIS-C. The prevalence of diffuse skin rash, hand and foot edema or erythema and gastrointestinal signs was significantly higher in patients hospitalized with KD/MIS-C. There was no significant difference in laboratory findings between the two groups. Coronary artery dilation was more frequently observed in patients with KD/MIS-C compared to those with KD (40.5% vs. 14.6%, P = 0.009).
