Fatal Doudenal Ulcer Bleeding in Status Asthmaticus Treated with Theophylline and Steroids.
- Author:
Sang Woo LEE
1
;
Chang Keun KIM
;
Churl Young CHUNG
;
Young Doug KIM
Author Information
1. Department of Pediatrics, College of Medicine, Inje University Sanggye Paik Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Theophylline;
Steroids;
Status asthmaticus;
Bleeding duodenal ulcer
- MeSH:
Abdominal Pain;
Adrenal Cortex Hormones;
Child;
Duodenal Ulcer;
Emergencies;
Hematemesis;
Hemorrhage*;
Humans;
Male;
Nausea;
Status Asthmaticus*;
Steroids*;
Theophylline*;
Ulcer*;
Vomiting
- From:Journal of the Korean Pediatric Society
1998;41(4):548-552
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is generally agreed that theophylline preparations and steroids should be given intravenously for status asthmaticus. Theophylline can potentially have adverse gastrointestinal effects including abdominal pain, nausea, vomiting, and hematemesis. Upper gastrointestinal bleeding in patients treated with corticosteroids without a past history of upper gastrointestinal bleeding has been reported rarely. But the etiologic significance of the stress of status asthmaticus, administration of theophylline or corticosteroids in the development of ulcer has been open to question. We report a case of 8-year-old boy with status asthmaticus treated with these medications and later found to have a bleeding duodenal ulcer for which emergency surgery was necessary.
