Exercise With a Novel Digital Device Increased Serum Anti-influenza Antibody Titers After Influenza Vaccination
- Author:
Jun-Pyo CHOI
1
;
Ghazal AYOUB
;
Jarang HAM
;
Youngmin HUH
;
Seung Eun CHOI
;
Yu-Kyoung HWANG
;
Ji Yun NOH
;
Sae-Hoon KIM
;
Joon Young SONG
;
Eu Suk KIM
;
Yoon-Seok CHANG
Author Information
- Publication Type:Original Article
- From:Immune Network 2023;23(2):e18-
- CountryRepublic of Korea
- Language:English
- Abstract: It has been reported that some exercise could enhance the anti-viral antibody titers after vaccination including influenza and coronavirus disease 2019 vaccines. We developed SAT-008, a novel digital device, consists of physical activities and activities related to the autonomic nervous system. We assessed the feasibility of SAT-008 to boost host immunity after an influenza vaccination by a randomized, open-label, and controlled study on adults administered influenza vaccines in the previous year. Among 32 participants, the SAT-008 showed a significant increase in the anti-influenza antibody titers assessed by hemagglutination-inhibition test against antigen subtype B Yamagata lineage after 4 wk of vaccination and subtype B Victoria lineage after 12 wk (p<0.05). There was no difference in the antibody titers against subtype “A.” The SAT-008 also showed significant increase in the plasma cytokine levels of IL-10, IL-1β, and IL-6 at weeks 4 and 12 after the vaccination (p<0.05). A new approach using the digital device may boost host immunity against virus via vaccine adjuvant-like effects.
