Arcuate Nucleus of the Hypothalamus:Anatomy, Physiology, and Diseases

Author: Juhyun SONG ¹ ; Seok-Yong CHOI
Author Information

1. Department of Anatomy, Chonnam National University Medical School, Hwasun 58128, Korea
Publication Type:Review Article
From:Experimental Neurobiology 2023;32(6):371-386
CountryRepublic of Korea
Language:English
Abstract: The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained. As such, dysfunction of the ARH can lead to disorders of nutrition/metabolism and reproduction. Here, we review various types of neurons in the ARH and several genetic disorders caused by mutations in the ARH.