Brain Neuroplasticity after Treatment with Antiseizure: A Review

Author: Débora Lopes Silva de SOUZA ¹ ; Hosana Mirelle Goes e Silva COSTA ; Francisca Idalina NETA ; Paulo Leonardo Araujo de Gois MORAIS ; Luís Marcos de Medeiros GUERRA ; Fausto Pierdoná GUZEN ; Lucídio Clebeson de OLIVEIRA ; José Rodolfo Lopes de Paiva CAVALCANTI ; Cynthia Cavalcanti de ALBUQUERQUE ; Claudio Lopes de VASCONCELOS
Author Information

1. Faculty of Health Sciences, Department of Biomedical Sciences, Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil
Publication Type:Review
From:Clinical Psychopharmacology and Neuroscience 2023;21(4):665-675
CountryRepublic of Korea
Language:English
Abstract: Epilepsy is a disease characterized by the periodic occurrence of seizures. Seizures can be controlled by antiseizure medications, which can improve the lives of individuals with epilepsy when given proper treatment. Therefore, this study aimed to review the scientific literature on brain neuroplasticity after treatment with antiseizure drugs in different regions of the brain. According to the findings, that several antiseizure, such as lamotrigine, diazepam, levetiracetam, and valproic acid, in addition to controlling seizures, can also act on neuroplasticity in different brain regions. The study of this topic becomes important, as it will help to understand the neuroplastic mechanisms of these drugs, in addition to helping to improve the effectiveness of these drugs in controlling the disease.