Infection Status of Common Infectious Diseases among Patients in Specialized Cancer Hospital
10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2024.0419
- VernacularTitle:肿瘤专科医院2022年就诊患者常见传染病感染状况分析
- Author:
Yuanyuan ZHANG
1
;
Haozhi ZHU
;
Nansong XU
;
Jindun YU
;
Chuangzhong DENG
;
Lihua HUANG
Author Information
1. 华南恶性肿瘤防治全国重点实验室//广东省恶性肿瘤临床医学研究中心//中山大学肿瘤防治中心,广东 广州 510060
- Keywords:
specialized cancer hospital;
patients;
infectious diseases;
infection status;
screening;
diagnosis
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2024;45(4):666-672
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To understand the current status of human immunodeficiency virus(HIV),Treponema palli-dum(TP),hepatitis C virus(HCV)and hepatitis B virus(HBV)infections among patients undergoing screening tests in a specialized cancer hospital in South China,and to analyze the completion of further testing for confirmation,so as to pro-vide a reference for management of common infectious diseases and prevention of nosocomial infections.[Methods]We ana-lyzed the positive rates of HIV antigen/antibody combination assay(HIV-comb),TP antibody(anti-TP),HCV antibody(anti-HCV)and hepatitis B surface antigen(HBsAg)among the outpatients and inpatients who underwent the screening tests in 2022.Then we examined the percentage of those patients with seropositivity for further confirmation.[Results]In patients who underwent the screening tests,the positive rate,percentage of patients for further confirmation test and over-all prevalence for HIV-comb were were 0.07%,100%and 0.06%,respectively;for Anti-PT 1.99%,100%and 0.51%,respectively.Positive rate of anti-HCV was 0.90%and 26.61%of patients completed further HCV RNA quantitative as-say,in 26.44%of whom,HCV RNA levels were above the detection limit.Positive rate of HBsAg was 21.06%and 54.40%of patients completed further HBV DNA quantitative assay,in 51.60%of whom,HBV DNA levels were above the detec-tion limit.As for the nucleic acid testing among the suspected hepatitis patients,we found smaller coverage in outpatients than in inpatients and larger coverage in liver cancer patients than in other patients.[Conclusions]Compared with general population,patients in this specialized cancer hospital had similar infection levels of HIV and syphilis,and 100%of them completed further confirmation testing.Hepatitis C and hepatitis B infections were at a relatively high level,but which could not accurately reflect the level of virus replication due to insufficient coverage of nucleic acid testing.Specialized can-cer hospitals should prompt medical staff to attach more importance to screening and further confirmation of common infec-tious diseases among tumor patients.While offering anti-cancer treatment,hospitals should also actively refer the con-firmed cases with infectious diseases to designated or general hospitals for a better outcome and quality of medical services.
