The COVID-19 pandemic, coupled with societal and technological changes around the globe, demanded adaptations to nursing education. This educational case report is an idiographic narrative of an institution’s experience of shifting to flexible learning in nursing education in the Philippines during the COVID-19 pandemic. Various subjects, involving foundation, intervention, and intensive nursing courses, were implemented in flexible learning modes during the Academic Year 2020 to 2021. This case report identified how curricular integration and curricular redesign were carried out to ensure the achievement of BSN Program Outcomes. Faculty development on flexible learning was implemented with training outcomes to include the application of key concepts and instructional design principles toward flexible learning. Training outcomes were evaluated through embedded activities on course package development by the faculty participants. This case report also identified various teaching-learning strategies, and how they addressed emerging issues, including differences in technological competence and accessibility. The report highlighted how the college transitioned to flexible learning through curriculum integration and course redesign which has been effective and efficient in the achievement of educational outcomes. Appropriate training and guidance of the faculty to enable them to integrate and redesign courses, and address emerging issues and challenges, could help in the transition to flexible learning. Flexible learning is an effective pedagogical approach to implementing nursing education. Timely implementation of measures must be taken to ensure relevant and appropriate curricular integration and redesign of courses, and consequently, the nursing program.