Analysis of clinical characteristics of nerve injury caused by the abuse of nitrous oxide (N2O)
- VernacularTitle:一氧化二氮(N2O)滥用导致神经损伤的临床特点分析
- Author:
Caixia LIU
1
;
Qiuhui CHEN
1
;
Zhimin TIAN
1
Author Information
- Publication Type:Journal Article
- Keywords: Nitrous oxidetoxicity; Subacute combined degeneration; Vitamin B12; Megaloblastic anemia; Homocysteine
- From: Journal of Apoplexy and Nervous Diseases 2020;37(2):147-149
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze clinical features of nerve injury caused bythe abuse of nitrous oxide.Methods We retrospectively analyzed the clinical data of eight patients with nitrous oxide poisoning and summarized their clinical features.Results Eight patients with nitrous oxide poisoning were all young and middle-aged with a history of exposure to nitrous oxide.Peripheral nervous system was impaired in eight patients,central nervous system was impaired in five patients,autonomic nerve was impaired in two patients,and two patient had neuropsychiatric symptoms.Vitamin B12 deficiency and homocysteine elevation were detected in eight patients.High doses of vitamin B12,methylcobalamin or adenosine cobalamin were effective.Conclusion Long-term consumption of N2O can lead to megaloblastic anemia,nervous system injury and even fatal.
- Full text:2024080215184738968Analysis of clinical characteristics of nerve injury caused by the abuse of nitrous oxide N2O).pdf
