Correlation between serum Adropin protein and severity and prognosis of patients with hypertensive intracerebral hemorrhage
- VernacularTitle: 血清Adropin蛋白与高血压脑出血患者病情严重程度及预后的相关性分析
- Author:
Weidong QIAO
1
;
Zhenzhong JIANG
1
;
Wang YUN
1
Author Information
- Publication Type:Journal Article
- Keywords: Adropin protein ； Hypertension ； Cerebral hemorrhage ； Prognosis
- From: Journal of Apoplexy and Nervous Diseases 2020;37(2):104-107
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the correlation between serum Adropin protein expression and the severity and prognosis of patients with hypertensive intracerebral hemorrhage.Methods Patients with hypertensive intracerebral hemorrhage who were treated in our hospital from January 2016 to January 2018 were enrolled.One hundred patients were enrolled in the study group.One hundred healthy subjects were included as control group.Serum Adropin protein levels were measured and analyzed.The relationship between the levels of Adropin protein and the disease condition and prognosis in patients with hypertensive intracerebral hemorrhage.Results The study group finally included in 97 cases.The control group finally included in 99 cases.The expression levels of Adropin protein in the study group were lower than that in the control group (P<0.05).The expression levels of Adropin protein were significantly different in patients with different severity of disease (P<0.05).The expression levels of Adropin protein in patients with hypertensive intracerebral hemorrhage with different prognosis were statistically significant (P<0.05).Univariate analysis showed that age,severity of disease,amount of bleeding,and whether it broke into the ventricle were the prognostic factors of hypertensive cerebral hemorrhage (P<0.05).Multivariate logistic regression analysis showed that Adropin protein,age,severity of disease,and whether bleeding broke into the ventricle were independent factors affecting the prognosis of patients with hypertensive intracerebral hemorrhage (P<0.05).Conclusion Serum Adropin protein is associated with the severity and prognosis of patients with hypertensive intracerebral hemorrhage.Serum Adropin protein is an independent factor affecting the prognosis of patients with hypertensive intracerebral hemorrhage.
- Full text:2024080214351478182Correlation between serum Adropin protein and severity and prognosis of patients with hypertensive intracerebral hemorrhage.pdf
