Correlation analysis of serum procalcitonin and infarct volume in young patients with acute cerebral infarction
10.19845/j.cnki.zfysjjbzz.2020.0391
- VernacularTitle: 血清降钙素原与青年急性脑梗死患者梗死体积的相关分析
- Author:
Hai YU
1
;
Yingcong CHEN
1
;
Huijun WEN
1
Author Information
1. Department of Neurology,Baoji Municipal Central Hospital,Baoji,Shanxi 721008,China
- Publication Type:Journal Article
- Keywords:
Procalcitonin;
Acute cerebral infarction;
Young;
Infarct volume;
Neurological deficit
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(6):547-550
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the serum procalcitonin (PCT) levels in young patients with acute cerebral infarction (YACI) and study its relationship with the infarct volume of YACI patients.Methods According to the volume of cerebral infarction,YACI patients (observation group) who were admitted for the first time were divided into large cerebral infarction group（18 patients）,middle cerebral infarction group (31 patients),and small cerebral infarction group (37 patients).The severity of clinical symptoms was determined using the National Institute of Health Stroke Scale score.In addition,72 healthy young people with brain diffusion weighted imaging examinations within the normal range during the same period were selected as the control group.Serum procalcitonin levels were measured by enzyme-linked immune sorbent assay (ELISA).The relationship among serum procalcitonin,young acute cerebral infarction volume and NIHSS score was analyzed.Results Serum PCT levels in observation group were significantly higher than those in control group,NIHSS of severe group were significantly higher than those of mild group.The levels of PCT in large infarction group was higher than that in middle infarction group and small infarction group,while the levels of PCT in middle infarction group was higher than that in small infarction group.PCT levels were positively correlated with NIHSS score and infarct volume in the observation group.Conclusion The levels of serum PCT in YACI patients may be related to the inflammatory reaction of the cerebral artery after cerebral infarction and positively related to the volume of cerebral infarction and NIHSS score.PCT concentration can predict the disease severity of YACI patients,and is of clinical application value.
- Full text:2024080122585297456Correlation analysis of serum procalcitonin and infarct volume in young patients with acute cerebral infarction.pdf
