The risk factors analysis of cerebral microbleeds in patients with white matter hyperintensities
10.19845/j.cnki.zfysjjbzz.2020.0376
- VernacularTitle: 缺血性脑白质高信号患者脑微出血的危险因素分析
- Author:
Hongyu CAO
1
;
Wei QIN
1
;
Lei YANG
1
Author Information
1. Department of Neurology,Beijing Huai-Rou Hospital，Beijing Chao-Yang Hospital,Capital Medical University,Beijing 101400,China
- Publication Type:Journal Article
- Keywords:
White matter hyperintensities;
Cerebral microbleed;
Risk factors;
Aspirin
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(6):485-489
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for cerebral microbleeds (CMBs) in patients with white matter hyperintensities (WMH),and to find out the correlation between the severity of cerebral microbleeds and the duration of taking aspirin in patients with white matter hyperintensities.Methods We collected patients with white matter hyper-intensities confirmed by MRI，who were admitted to the neurology department of Beijing Chaoyang Hospital Affiliated to Capital Medical University from June 2016 to September 2017.All enrolled patients were divided into non-CMBs group,mild CMBs group and moderate to severe CMBs group.All patients’ clinical data were collected for analyzing the risk factors of CMBs.Furthermore,the WMH patients who is taking aspirin were analyzed by subgroup analysis.Results A total of 357 WMH patients were enrolled in this study,including 189 patients in the non-CMBs group,94 in the mild-CMBs group,and 74 in the moderate to severe CMBs group.There were significant differences among the three groups in gender,acute ischemic stroke,the history of hypertension,the history of ischemic stroke,diastolic blood pressure on admission,taking aspirin for more than two years,homocysteine level and the severity of WMH (P<0.05).Results From subgroup analysis of 263 patients with WMH patients taking aspirin showed that with the increase of CMBS,the percentage of severe WMH patients increased gradually,and the percentage of patients taking aspirin for more than 2 years increased gradually as well.Conclusions The severity of WMH is correlated with the severity of CMBs in WMH patients.Male,the history of hypertension and taking aspirin for more than two years are risk factors for CMBs in WMH patients,and the longer duration of taking aspirin in WMH patients,the more severe CMBs are.
- Full text:2024080122182197397The risk factors analysis of cerebral microbleeds in patients with white matter hyperintensities.pdf
