Efficacy of Naomaili granule in the treatment of different subtypes of acute cerebral infarction
- VernacularTitle: 脑脉利颗粒治疗不同亚型急性脑梗死的临床疗效观察
- Author:
Ming ZHANG
1
;
Jie SUN
1
;
Hongjiang GUO
1
Author Information
- Publication Type:Journal Article
- Keywords: Acute cerebral infarction; TOAST type; Naomaili granule; NIHSS score; Barthel Index
- From: Journal of Apoplexy and Nervous Diseases 2020;37(7):638-640
- CountryChina
- Language:Chinese
- Abstract: Objective To study the efficacy and safety of Naomaili granule in patients with different subtypes of acute cerebral infarction. Methods A total of 122 hospitalized patients with acute cerebral infarction from June to December 2019 were randomly divided into control group （n=56） and observation group （n=66）. The control group was treated according to the guidelines for the diagnosis and treatment of acute ischemic stroke，while the observation group was treated with Naomaili granule besides the guidelines. The two groups were classified according to the TOAST criteria. Before and after treatment，NIHSS score and BI score were compared，and adverse reaction was evaluated. Results Compared with the control group，the NIHSS score of observation group was decreased while BI score was increased after 21 days of treatment （P<0.05）. After the treatment，the NIHSS score of the subtype of large-artery therosclerosis（LAA）、small-artery occlusion（SAO）、cardioembolism（OD）、otherdetermined cause（OD）and undetermined cause（UND）was decreased while BI scores was increased（P<0.05）. However，LAA subtype improved more obviously（P<0.05），while the change of CE subtype had no statistical significance（P>0.05）. Conclusion Naomaili granule has a good effect on acute cerebral infarction and it can improve the nervous function and activities of daily living for the subtypes of LAA，SAO，OD and UND according to the TOAST criteria.
- Full text:2024080122070957037Efficacy of Naomaili granule in the treatment of different subtypes of acute cerebral infarction.pdf
