Clinical application of 3D ASL in the evaluation of early cerebral hemodynamic changes in patients with leukoaraiosis
10.19845/j.cnki.zfysjjbzz.2020.4038
- VernacularTitle:3D ASL在脑白质疏松患者早期脑血流动力学变化评估中的临床应用
- Author:
Jianguo ZHOU
1
;
Dayong FU
1
;
Mingcong LU
1
Author Information
1. Department of Radiology,Nanjing University of Chinese Medicine Affiliated Lianyungang Hospital,Lianyungang 222004,China
- Publication Type:Journal Article
- Keywords:
Leukoaraiosis ； Cerebral watershed ； Arterial spin labeling ； Cerebral blood flow
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(8):732-734
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of 3D artistic spin labeling technology in evaluating early perfusion changes of leukaraiosis.Methods Ninety patients and 30 healthy volunteers with different degrees of LA who were examined by magnetic resonance imaging were collected from January 2018 to April 2020.According to the Fazekas scale,they were divided into LA0,LA1,LA2 and LA3 group,30 cases were included in each group.CBF values of cortical watershed and subcortical watershed were measured according to cerebral blood flow pseudocolor image,and cerebral perfusion differences in anterior,posterior,radial crown and semicircular center of cortical watershed in different LA grades were evaluated,and the characteristics of early hemodynamic changes of LA were analyzed.Results The CBF values of LA2,LA3 were significantly lower than that of LA0.There was no significant difference between LA1 and LA0 (P>0.05),however,the CBF in subcortical watershed was slightly lower than LA0 (P<0.05).Conclusion 3D ASL perfusion imaging technology can be used to quantify the CBF in the watershed area,and can be used to monitor the state of cerebral perfusion in LA patients.The CBF response in the subcortical watershed area is more sensitive,which can be used to evaluate the early cerebral hemodynamic changes in LA.
- Full text:2024080120140901686Clinical application of 3D ASL in the evaluation of early cerebral hemodynamic changes in patients with leukoaraiosis.pdf
