Predictive value of new inflammatory markers in blood routine examination for the prognosis of acute cerebral infarction
10.19845/j.cnki.zfysjjbzz.2020.4035
- VernacularTitle:血常规中炎症指标在脑梗死预后中的预测价值
- Author:
Cuihong MA
1
;
Jiamin JIN
1
;
Junlian ZHANG
1
Author Information
1. Chengde Central Hospital,Hebei,Chengde 067000,China
- Publication Type:Journal Article
- Keywords:
Acute cerebral infarction ； Inflammatory markers； Neutrophil to lymphocyte ratio ； Platelet to lymphocyte ratio ； Prognosis
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(8):720-724
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognostic value of NLR,PLR,PNR and PWR in acute cerebral infarction.Methods We enrolled 139 patients who were diagnosed with acute cerebral infarction from Chengde Central Hospital from September 2018 to September 2019.Routine blood test results were collected.Patients were divided into mild stroke and moderate-severe stroke groups according to the NIHSS at admission.After three months,subjects were divided into two groups according to the modified Rankin score (mRS),one group with good prognosis (mRS 0~2) and the other with poor prognosis (mRS 3~6).Logistic regression analysis was performed,the ROC curve was used to evaluate inflammatory markers in predicting prognosis.Results After adjusting for confounders,PLR and NLR in the group with good prognosis were significantly lower than that of the other group (P<0.005),PWR was higher in good prognosis group (P<0.05).In addition,PLR and NLR in the mild stroke group were significantly lower than the moderate-severe stoke group (P<0.05).The ROC curve showed that the area under the curve of PLR and NLR for predicting the prognosis of acute cerebral infarction at 3 months was 0.721 (95%CI 0.630~0.813;P<0.001),0.765 (95%CI 0.678~0.851;P<0.001) and the area under the curve of the PWR is 0.642.Conclusion NLR and PLR,as new inflammatory indicators,may be independent factors for predicting the prognosis of AIS,and can also be used to judge the severity of stroke.
- Full text:2024080120075497510Predictive value of new inflammatory markers in blood routine examination for the prognosis of acute cerebral infarction.pdf
