Analysis of influencing factors of early neurological deterioration in acute cerebral infarction patients with middle cerebral artery occlusion
10.19845/j.cnki.zfysjjbzz.2020.0429
- VernacularTitle: 大脑中动脉闭塞致急性脑梗死患者早期神经功能恶化的影响因素分析
- Author:
Liyong ZHANG
1
;
Xueying SHI
1
;
Xiangyang TANG
1
Author Information
1. Department of Neurology,Anqing Hospital Affiliated to Anhui Medical University,Anqing 246003,China
- Publication Type:Journal Article
- Keywords:
Middle cerebral artery occlusion;
Acute cerebral infarction;
Early neurological deterioration;
Influencing factors
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(8):699-703
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the influencing factors of early neurological deterioration in acute cerebral infarction patients with middle cerebral artery (MCA) occlusion.Methods One hundred and thirty-four acute cerebral infarction patients with MCA occlusion in the department of neurology of our hospital from January 2017 to December 2019 were enrolled retrospectively.The definition of early neurological deterioration (END) was the national institutes of health stroke scale (NIHSS) score increased by ≥ 2 compared with the baseline NIHSS score of admission within 72 hours.Forty-eight cases in END group and 86 cases in non-END group.Baseline and clinical data at admission were compared between the two groups.Binary multivariate logistic regression analysis were used to assess the influencing factors of END in acute cerebral infarction patients with MCA occlusion.Results (1)Gender,age,time of onset,admission NIHSS score,collateral circulation and parameters of blood pressure variability (SBPsd,SBPcv,SBPmax-min,DBPsd,DBPcv,DBPmax-min) were statistically significant between non-END group and END group.(2)Multivariate logistic regression analysis suggested that poor collateral circulation(OR=8.330，95%CI 1.629~42.587,P=0.011) and SBPmax-min (OR=1.139,95%CI 1.032~1.258,P=0.01) were independent risk factors for END in acute cerebral infarction patients with MCA occlusion.SBPmax-min predicted effectively END with best cutoff value 35.5,sensitivity 93.8%,specificity 64% and AUC0.85 (95%CI 0.788~0.912,P<0.001).Conclusion There were many factors affecting END in patients with acute cerebral infarction with MCA occlusion.Poor collateral circulation and Blood pressure variability (BPV) were independent risk factors for END.
- Full text:2024073122440473775Analysis of influencing factors of early neurological deterioration in acute cerebral infarction patients with middle cerebral artery occlusion.pdf
