A single center study on the relationship between white matter hyperintensities and right to left shunt in migraine patients in Fujian
- VernacularTitle:偏头痛患者脑白质高信号与右向左分流相关性的福建地区单中心研究
- Author:
Pan LIN
1
;
Mingjing JIANG
1
;
Yuanqin CHEN
1
Author Information
- Publication Type:Journal Article
- Keywords: Migraine; White matter hyperintensities; Right to left shunt; Transcranial doppler ； Bubbles test
- From: Journal of Apoplexy and Nervous Diseases 2020;37(9):823-827
- CountryChina
- Language:Chinese
- Abstract: Objective To observe the incidence of white matter hyperintensities （WMHs） and the distribution of right to left shunt （RLS） in migraine patients，and to explore whether WMHs is related to RLS. Methods 106 patients with migraine were selected as the research objects. The basic data and clinical information of migraine were collected. The WMHs were evaluated by cranial MRI. The RLS was diagnosed and graded by transcranial Doppler （TCD） bubbles test. The correlation between WMHs and RLS was analyzed. Results Among 106 migraine patients，33 （31.1%） were in WMHs+ group and 73 （68.9%） in WMHs- group. The total positive rate of RLS was 48.1% （51/106）. The distribution of different shunt levels was as follows：grade Ⅰ shunt in 27 cases （25.5%），grade Ⅱ shunt in 4 cases （3.8%），grade Ⅲ shunt in 6 cases （5.6%），grade Ⅳ shunt in 14 cases （13.2%）. In "WMHs+" group，there were 5 cases of grade Ⅰ shunt，1 case of grade Ⅱ shunt，3 cases of grade Ⅲ shunt and 10 cases of grade Ⅳ shunt；in "WMHs-" group，there were 22 cases of grade Ⅰ shunt，3 cases of grade Ⅱ shunt，3 cases of grade Ⅲ shunt and 4 cases of grade Ⅳ shunt. Compared with "WMHs+" group and "WMHs-" group，there was no statistical difference in the overall positive rate of bubbles test between the two groups （P>0.05，χ2=1.719），but the large shunt rate of "WMHs+" group was significantly higher than that of "WMHs-" group （P<0.01，χ2=13.188）. Conclusion There is no significant correlation between WMHs and RLS in migraine patients，but large RLSs will increase the risk of WMHs in migraine patients.
- Full text:2024073122151603187A single center study on the relationship between white matter hyperintensities and right to left shunt in migraine patients in Fujian.pdf
