Analysis of clinical-encephalogram characteristics of 134 MRI-negative adult epilepsy
- VernacularTitle:134例MRI阴性成人癫痫患者临床-脑电图特征分析
- Author:
Xinxin LI
1
;
Haogang SUN
1
;
Qing ZHENG
1
Author Information
- Publication Type:Journal Article
- Keywords: Epilepsy ； 3.0TMRI-negative ； Etiology ； Multimodal imaging
- From: Journal of Apoplexy and Nervous Diseases 2020;37(9):809-812
- CountryChina
- Language:Chinese
- Abstract: Objective Analyze and summarize the clinical and EEG characteristics of 3.0 T MRI-negative adult patients with epilepsy，to provide a basis for improving the etiology of MRI-negative adult patients with epilepsy. Methods Review the clinical data of patients with epilepsy diagnosed and treated in our hospital from September 2016 to June 2019，aged ≥16 years old and with a cranial 3.0T MRI result normal，combined with relevant literature，to summarize and analyze MRI-negative adult epilepsy patients Clinical and EEG characteristics，to explore possible potential causes. Results 134 MRI-negative adult epilepsy patients had the most common onset at 18～60 years old，accounting for 64.18%，37.31% of patients had a traceable etiology；50.75% of patients had clear aura symptoms before onset，and the specific aura symptoms were significantly higher than non-specific aura symptoms. The seizure type was most common with focal origin；82.10% of patients were treated with standardized AEDs，and the effective rate was 67.27%；68.18% of them were monotherapy，with a total effective rate of 54.54%. The positive rate of epilepsy detected by video-EEG was 62.69%. Intermittent abnormal discharges were most common in the temporal region，accounting for 40.48%，and were mostly were unilateral. Conclusion MRI-negative adult epilepsy is more common in young and middle-aged patients，and it is mostly of focal origin. The temporal lobe epilepsy has the highest proportion. The potential etiology is complex and diverse. regular anti-epileptic treatment should be used，and immunization and multimodal imaging should be completed as soon as possible to find the cause of intervention.
- Full text:202407312203214892Analysis of clinical-encephalogram characteristics of 134 MRI-negative adult epilepsy.pdf
