The research of PDMS⁃CHXG coating construction and antibacterial properties on abutment surface
10.19405/j.cnki.issn1000-1492.2022.10.006
- Author:
Chenchen Li
1
;
Rong Xia
1
;
Shimeng Pang
1
;
Jinlan Yu
1
Author Information
1. Dept ofStomatology, The Second Affiliated Hospital ofAnhui Medical University, Hefei 230601
- Publication Type:Journal Article
- Keywords:
implant denture;
abutment;
polydimethylsiloxane;
chlorhexidine gluconate;
Porphyromonas gingival⁃ is;
antibacterial properties
- From:
Acta Universitatis Medicinalis Anhui
2022;57(10):1542-1546
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore the antibacterial coating of polydimethylsiloxane⁃chlorhexidine gluconate (PDMS⁃CHXG) constructed on the smooth titanium surface and antibacterial properties for Porphyromonas gingivalis of CHXG solution with different concentrations.
Methods :The titanium was polished to 7 000 mesh to mirror shape of abutment, cleaned and dried, then treated with alkalization. The samples were randomly divided into 5 groups: blank control group (C), test groups: grafted CHXG concentration of 0 (T0 ), 0. 4 (T1 ), 0. 8 (T2 ), 1. 6 mg/ml (T3 ) . The surface structural changes were observed by cold field emission scanning electron microscope (CFESEM), and the component elements of coating were analyzed semi⁃quantitatively. The antibacterial properties of the coating were evaluated by antibacterial zone, live/dead bacteria staining and crystal violet experiments.
Results:A dense film was formed on the surface of titanium under the CFESEM compared with C group. The content of Cl element increased with the increase of CHXG concentration. There was no inhibition zone around the samples in C and T0 groups, but it was found in T1 , T2 and T3 groups. Live/dead bacteria staining showed no viable bacteria in the T2 and T3 groups. The results of crystal violet staining showed that T1 , T2 and T3 groups were statistically different from C and T0 groups, but the difference between the groups T2 and T3 was not statistically significant.
Conclusion :The antibacterial coating of PDMS⁃CHXG is constructed successfully. The PDMS⁃CHXG coating displays an exceptional antibacterial property when the concentration of CHXG reaches 0. 8 mg/ml.
- Full text:2024073122021986727基台表面抗菌涂层PDMS-...XG的构建及抗菌性能的研究_李趁趁.pdf
