Clinical analysis of 26 cases of dementia with Lewy bodies
10.19845/j.cnki.zfysjjbzz.2020.0486
- VernacularTitle:路易体痴呆26例临床分析
- Author:
Chaowei WANG
1
;
Sibei JI
1
;
Yanxia LIU
1
Author Information
1. The First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,China
- Publication Type:Journal Article
- Keywords:
Lewy body disease / Dementia;
Magnetic resonance imaging;
Positron-emission tomography
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(10):924-926
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and neuroimaging features of dementia with Lewy bodies (DLB).Methods The clinical data of 26 patients with DLB were retrospectively analyzed.Results The initial symptoms were cognitive symptoms (65%),Parkinsonism (19%),or both.In the clinical manifestations,38% of patients showed fluctuating cognition,77% showed Parkinsonism,62% showed hallucinations,and 50% showed rapid eye movement sleep behavior disorder,65% showed severe autonomic dysfunction.59% of the patients revealed the preservation of hippocampal structures on MRI scan.In addition,FDG PET showed hypo-metabolism in bilateral parietal and occipital lobe in 7 patients,and CFT PET demonstrated reduced dopamine transporter uptake in the basal ganglia in 2 patients.Conclusion Cognitive impairment was the initial symptoms in most patients with DLB,and the clinical symptoms were characterized by Parkinsonism,hallucinations,rapid eye movement sleep behavior disorder and psychiatric symptoms.Neuroimaging examination including MRI and PET scan were useful to diagnose.
- Full text:2024073120252836354Clinical analysis of 26 cases of dementia with Lewy bodies.pdf
