- VernacularTitle:急性脑梗死的认知功能障碍特点分析
- Author:
Dan LI
1
;
Ting LIU
1
;
Jia LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Acute phase of cerebral infarction; Infarction location; Cognitive dysfunction; Neuropsychological scale
- From: Journal of Apoplexy and Nervous Diseases 2020;37(11):1016-1020
- CountryChina
- Language:Chinese
- Abstract: Objective Exploring the incidence of cognitive dysfunction after acute cerebral infarction and analyse the characteristics of cognitive domain damage in different infarct sites. Methods Selected from January 2016 to January 2019 213 patients with acute cerebral infarction treated by the Department of Encephalopathy,Chinese Medical Hospital of Xinjiang Medical University,according to theneuropsychological scale scores divided into three groups as follow:normal cognitive group (NCI,n=46),post-stroke cognitive impairment not dementia group(PSCIND,n=91),and poststroke dementia group(PSD,n=76). Clinical data and imaging data,The neuropsychological scale was evaluated. Results The incidence of cognitive dysfunction in patients with acute cerebral infarction reached 78.4%;MMSE score showed that the delayed recall ability of non-dominant cerebral infarction was significantly impaired[non-dominance/dominance (1.80±1.05)/(1.55±1.11);P=0.025];Frontallobes infarction impaired language recapitulation [Yes/No (0.32±0.30)/(0.63±0.41);P=0.008];Immediate memory [Yes/No(1.91±1.09)/(2.99±1.12);P=0.04] and verbal repetition [Yes/No(0.22±0.3)/(0.59±0.5);P=0.012] of parietal infarction was significantly damaged. The MOCA score showed that the total MOCA score of non-dominant cerebral infarction was higher than the advantage side brain [Non-advantage/Advantage (17.54±6.65)/(16.65±6.40);P=0.041]. Language function of the cerebral infarction on the dominant side is significantly impaired [Non-advantage/Advantage:(1.66±1.10)/(1.22±0.98) Score;P=0.004]. Delayed recall ability was significantly impaired in non-dominant cerebral infarction [non-dominance/advantage:(1.55±1.45)/(0.97±1.37);P=0.010]. Language function[Yes/No:(1.41±0.91)/(2.32±1.02) points;P=0.014],named [Yes/No:(1.90±1.03)/(2.94±1.26);P=0.019]and orientation[Yes/No:(2.15±1.10)/(4.28±1.36) points;P=0.000]were significant damaged in frontal infarction;delayed recall [Yes/No:(1.32±1.10)/(0.91±0.94) points;P=0.000],attention [Yes/No:(2.2±0.4)/(2.5±0.6) points;P=0.038],language [Yes/No:(1.5±1.2)/(2.3±1.1);P=0.009]were significant damaged in parietal infarction. Language function[Yes/No:(1.52±1.31)/(2.52±1.06) points;P=0.001],orientation[Yes/No:(2.73±1.37)/(3.71±1.68) points;P=0.006]were significant damaged in basal ganglia infarction. The results of multivariate regression analysis showed:frontal lobe(P=0.008),temporal lobe(P=0.020),cerebellum(P=0.008) infarction increased risk of cognitive dysfunction. Conclusion The damage of different cognitive domains in patients with acute stage of cerebral infarction is related to the infarct site;The characteristics of cognitive domain damage were correlated with the infarct site;Infarction of the frontal,temporal and cerebellum increases the incidence of cognitive dysfunction.
- Full text:2024073115351243289急性脑梗死的认知功能障碍特点分析.pdf