Comparative study of endovascular therapy in patients with large artery atherosclerosis and cardiogenic acute posterior circulation occlusion
10.19845/j.cnki.zfysjjbzz.2020.0521
- VernacularTitle: 大动脉粥样硬化性和心源性急性后循环大血管闭塞患者血管内治疗的疗效对比研究
- Author:
Fulei CHEN
1
;
Linzhi DAI
1
;
Licang ZHU
1
Author Information
1. The First Affiliated Hospital,School of Medicine,Shihezi University,Shihezi 832000,China
- Publication Type:Journal Article
- Keywords:
Acute ischemic stroke;
Posterior circulation;
Intravascular therapy;
Large artery atherosclerosis;
Cardioembolism
- From:
Journal of Apoplexy and Nervous Diseases
2020;37(12):1070-1074
- CountryChina
- Language:Chinese
-
Abstract:
Objective In this study,the clinical data of single-center acute posterior circulation stroke patients were analyzed to compare the efficacy of TOAST classification for large artery atherosclerosis (LAA) and cardioembolism (CE) stroke patients after intravascular treatment difference.Methods Patient data comes from the advanced stroke center of the First Affiliated Hospital of Shihezi University School of Medicine,Xinjiang,China.According to the TOAST classification,the 98 people included were divided into LAA group and CE group.The mTICI score was used to evaluate vascular recanalization,the 90 day mRS score was used to evaluate the prognosis,the incidence of intracranial hemorrhage conversion within 72 hours and 90 day mortality Assess the safety of intravascular treatment.Results Among the 98 patients included in the study,79 were LAA stroke patients and 19 were CE patients.Compared with CE patients,LAA stroke patients are younger (60.08±12.64 vs 71.05±10.42,P=0.001),have a higher prevalence of hyperlipidemia (55.7% vs 22.1%,P=0.014),and preoperative systolic blood pressure higher (149.25±21.24 vs 134.79±22.83,P=0.010),lower NIHSS score (17.3 vs 22.2,P=0.025),better collateral circulation (ASITN/SIR score of 2~4 ratio,63.3% vs 21.1 %,P=0.002),the angioplasty rate is higher (31.6% vs 5.3%,P=0.040).However,the EVT recanalization rate (87.5% vs 84.2%,P=1.000) of the two groups of patients,the 90 day neurological function recovery rate (mRS score 0~2) (58.2% vs 36.8%,P=0.093),The incidence of postoperative intracranial hemorrhage transformation (1.3% vs 0%,P=1.000) and the 90 day stroke-related mortality (20.3% vs 42.1%,P=0.091) were not statistically significant.Conclusion s Although there were differences in baseline clinical data and clinical characteristics of EVT treatment between LAA and CE in posterior circulation,there was no significant difference in prognosis.
- Full text:2024073114425303753Comparative study of endovascular therapy in patients with large artery atherosclerosis and cardiogenic acute posterior circulation occlusion.pdf