Antimicrobial Management of Neonatal Sepsis.
10.5385/jksn.2012.19.2.53
- Author:
Ellen Ai Rhan KIM
1
Author Information
1. Division of Neonatology, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea. arkim@amc.seoul.kr
- Publication Type:Review
- Keywords:
Neonate;
Sepsis;
Antibiotics;
Therapeutic drug monitoring;
Resistance
- MeSH:
Anti-Bacterial Agents;
Cohort Studies;
Drug Monitoring;
Humans;
Infant;
Infant, Low Birth Weight;
Infant, Newborn;
Intensive Care Units;
Sepsis
- From:Journal of the Korean Society of Neonatology
2012;19(2):53-64
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neonatal infections are frequent complications of neonates receiving intensive care unit. In particular, large cohort study has suggested that neonatal infections among extremely low birth weight infants are associated with poor neurodevelopmental and growth outcomes in early childhood. This review article will focus on the rational use of empirical antibiotics/antifungal therapy for early and late onset sepsis/fungemia, duration of antibiotic treatment, highlight clinically relevant aspects of the antibiotics commonly used in the treatment of sepsis, antibiotics requiring therapeutic dose monitoring, and management of antibiotic-resistant infection in the neonate.
