Comparison of pain in patients with young-onset and late-onset Parkinson’s disease and analysis of influencing factors
10.19845/j.cnki.zfysjjbzz.2021.0029
- VernacularTitle: 早发型和晚发型帕金森病患者疼痛的比较及影响因素分析
- Author:
Chen YANG
1
;
Haiting YANG
1
;
Xingxing ZHENG
1
Author Information
1. Department of Neurology，Anhui Provincial Hospital Affiliated to Anhui Medical University，Hefei 230000，China
- Publication Type:Journal Article
- Keywords:
Parkinson’s disease;
Young-onset;
Late-onset;
Pain;
Nonmotor symptom
- From:
Journal of Apoplexy and Nervous Diseases
2021;38(2):122-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare pain in patients with young-onset (YOPD) and late-onset (LOPD) Parkinson’s disease and analyze influencing factors.Methods Seventy participants who visiting outpatient and inpatient of the neurology department of the Provincial Hospital Affiliated to Anhui Medical University from October 2018 to July 2020 were selected and divided into YOPD and LOPD group according to age and Hoehn-Yahr (H-Y) Scale.General data were collected.The king’s Parkinson’s disease pain scale (KPPS)，part 3 of the Unified Parkinson’s disease rating scale (UPDRS-Ⅲ).The hamilton rating scale for depression (HAMD） were used to assess the item of pain,motor function and prevalence of depression.And further analyses of their effects on pain were made.Results Compared with LOPD patients,YOPD patients had lower mean age,HAMA score and prevalence of hypertension and constipation,longer mean duration of disease,higher mean HAMD score,MMSE score,KPPS score and incidence of pain (P<0.05).Compared with LOPD patients with pain,YOPD patients with pain had higher prevalence of pain occurring in the waist,lower prevalence of pain occurring in the legs (P<0.05).YOPD patients with pain had higher mean UPDRS-Ⅲ score,HAMD score,HAMA score and dyskinesia stage than those without pain (P<0.05).LOPD patients with pain had higher mean HAMD score,HAMA score and dyskinesia stage than those without pain (P<0.05).Conclusion Patients with YOPD have a higher incidence of PD pain and more severe pain than those with LOPD.The more severe the emotional disorders and motor symptoms are,the more likely they will suffer from pain.Clinicians should standardize the treatment of pain according to the type and location of pain in PD patients,so as to improve the quality of life of patients.
- Full text:2024073023313324473早发型和晚发型帕金森病患者疼痛的比较及影响因素分析.pdf
