The value of 18F-FDG PET/CT dynamic imaging in the diagnosis of primary hepatocellular carcinoma with liver metastases
10.19405/j.cnki.issn1000-1492.2024.05.019
- VernacularTitle:18F-FDG PET/CT动态成像诊断原发性肝癌与肝转移瘤的价值
- Author:
Xin WANG
1
;
Zhenpeng YU
;
Hui WANG
;
Pengfei DAI
Author Information
1. 安徽医科大学第一附属医院核医学科,合肥 230022
- Keywords:
liver tumors;
positron emission tomography;
tomography;
X-ray computer;
fluorodeoxyglucose F18
- From:
Acta Universitatis Medicinalis Anhui
2024;59(5):869-873
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of 18F-FDG PET/CT dynamic imaging in the diagnosis of primary liver cancer and liver metastases.Methods In this study, the data of 94 patients with hepatic malignant lesions [hepa-tocellular carcinoma group (25 cases) , cholangiocellular carcinoma group (27 cases) , and liver metastases group (42 cases) ] imaged by whole-body dynamic 18 F-FDG PET/CT were used as the research subjects, and the meth-ods of (ANOVA) and subjects' working characteristic curves (ROC) were applied to examine the patients with liv-er malignant tumours of different pathological types SUVmax, MRFDG, TBR and dmax were statistically analysed as im-aging features.Results Among 94 patients, the differences in SUVmax, MRFDG, TBRSUVmax and TBRMRFDG were sta-tistically significant in the hepatocellular carcinoma, cholangiocellular carcinoma and hepatic metastasis groups (SUVmax: F =48.773, P <0.001; MRFDG: F =26.334, P <0.001; TBRSUVmax: F =41.314, P <0.001;TBRMRFDG:F=20.821, P<0.001).The AUCs for the differential diagnosis of primary hepatocellular carcinoma and hepatic metastases for SUVmax, MRFDG, TBRSUVmax, and TBRMRFDG were 0.836, 0.851, 0.827, and 0.847, re-spectively.There was a positive correlation between SUVmax, MRFDG, and the hepatic malignant lesions' There was a positive correlation between SUVmax, MRFDG and the maximum diameter dmax(SUVmax:r=0.4, P<0.05;MRFDG:r=0.2, P<0.05), and the difference was statistically significant.Conclusion 18F-FDG PET/CT dynamic ima-ging has good differential diagnostic efficacy in different pathological types of liver malignant tumors.There is a pos-itive correlation between SUVmax, MRFDG and dmax in different pathological types of liver malignant tumors.
- Full text:2024073022220373827_(18)F-FDG_PE...原发性肝癌与肝转移瘤的价值_王馨.pdf
