The value of 18 F ⁃FDG PET/CT dynamic imaging in the diagnosis of primary hepatocellular carcinoma with liver metastases
10.19405/j.cnki.issn1000-1492.2024.05.019
- Author:
Xin Wang
1
;
Zhenpeng Yu
1
;
Hui Wang
1
;
Pengfei Dai
1
Author Information
1. Dept of Nuclear Medicine , The First Afiliated Hospital of Anhui Medical University, Hefei 230022
- Publication Type:Journal Article
- Keywords:
liver tumors;
positron emission tomography;
tomography;
X ⁃ray computer;
fluorodeoxyglucose F18
- From:
Acta Universitatis Medicinalis Anhui
2024;59(5):869-873
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore the value of 18 F ⁃FDG PET/CT dynamic imaging in the diagnosis of primary liver cancer and liver metastases.
Methods :In this study , the data of 94 patients with hepatic malignant lesions [hepatocellular carcinoma group (25 cases) , cholangiocellular carcinoma group (27 cases) , and liver metastases group (42 cases)] imaged by whole⁃body dynamic 18 F ⁃FDG PET/CT were used as the research subjects , and the methods of (ANOVA) and subjects ′ working characteristic curves (ROC) were applied to examine the patients with liver malignant tumours of different pathological types SUV max , MRFDG , TBR and d max were statistically analysed as imaging features.
Results :Among 94 patients , the differences in SUV max , MRFDG , TBRSUV max and TBRMRFDG were statistically significant in the hepatocellular carcinoma , cholangiocellular carcinoma and hepatic metastasis groups (SUV max : F = 48. 773 , P < 0. 001 ; MRFDG : F = 26. 334 , P < 0. 001 ; TBRSUV : F = 41. 314 , P < 0. 001 ; TBRMRFDG : F = 20. 821 , P < 0. 001) . The AUCs for the differential diagnosis of primary hepatocellular carcinoma and hepatic metastases for SUV max , MRFDG , TBRSUV max , and TBRMRFDG were 0. 836 , 0. 851 , 0. 827 , and 0. 847 , respectively. There was a positive correlation between SUV max , MRFDG , and the hepatic malignant lesions ′ There was a positive correlation between SUV max , MRFDG and the maximum diameter d max (SUV max : r = 0. 4 , P < 0. 05 ; MRFDG :r = 0. 2 , P < 0. 05) , and the difference was statistically significant.
Conclusion :18 F ⁃FDG PET/CT dynamic imaging has good differential diagnostic efficacy in different pathological types of liver malignant tumors. There is a positive correlation between SUV max , MRFDG and d max in different pathological types of liver malignant tumors.
- Full text:2024073022220373827_(18)F-FDG_PE...原发性肝癌与肝转移瘤的价值_王馨.pdf
