Clinical and polysomnography findings in patients with Parkinson’s disease with restless leg syndrome
- VernacularTitle:帕金森病伴不宁腿综合征患者多导睡眠图的临床特征研究
- Author:
Shuyu SUN
1
,
2
;
Jinxiang CHENG
1
,
2
;
Jian QIU
1
,
2
Author Information
- Publication Type:Journal Article
- Keywords: Parkinson’s disease; Restless legs syndrome; Polysomnography
- From: Journal of Apoplexy and Nervous Diseases 2021;38(4):335-339
- CountryChina
- Language:Chinese
- Abstract: Objective To evaluate the differences of clinical and sleep characteristics and related factors between patients with Parkinson’s disease (PD) with restless leg syndrome (RLS) and idiopathic restless leg syndrome (iRLS).Methods One hundred and twenty-five patients with PD and 137 patients with iRLS from 2015 to 2020 were collected.PD patients were divided into PD with RLS group (PD-RLS) and PD without RLS group (PD-NRLS).The general condition,clinical features,subjective and objective sleep examination of the three groups were compared and analyzed.Results The prevalence of comorbid RLS in PD patients was 27.2%.The score of UPDRS-Ⅲ score in patients with PD-RLS was higher than that in PD-NRLS.The objective sleep quality of patients with PD-RLS was worse than that of patients with iRLS.Age and comorbid PD were the risk factors of poor sleep quality in patients with RLS.IRLS-RS and HAMD scores are risk factors for poor subjective sleep quality in patients with RLS.Conclusion Objective sleep disorders are more likely to occur in patients with PD-RLS than in patients with iRLS.While subjective sleep disorders in patients with iRLS are more severe.Which may be related to the clinical heterogeneity of RLS complicated with PD.
- Full text:2024073013232885242帕金森病伴不宁腿综合征患者多导睡眠图的临床特征研究.pdf