Relationship between total burden of small vessel disease and cognitive impairment in patients with atrial fibrillation related stroke
10.19845/j.cnki.zfysjjbzz.2021.0078
- VernacularTitle: 脑小血管病总体负担与房颤相关性卒中患者认知障碍的关系
- Author:
Xinyi MENG
1
;
Jinglei LV
1
;
Jie ZHOU
1
Author Information
1. The Affiliated Hospital of Qingdao University,Qingdao 266003,China
- Publication Type:Journal Article
- Keywords:
Cerebral small vessel disease;
Cognitive impairment;
Atrial fibrillation;
Stroke;
Magnetic resonance imaging;
Total burden
- From:
Journal of Apoplexy and Nervous Diseases
2021;38(4):301-305
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the overall burden of cerebral small vessel disease (CSVD) and cognitive impairment in patients with atrial fibrillation (AF) associated stroke.Methods Patients with acute cerebral infarction related to the cause of atrial fibrillation who were hospitalized in the Department of Neurology,Qingdao University Affiliated Hospital were collected from September 2018 to May 2020.According to the imaging findings of magnetic resonance imaging,the patients were divided into four groups:0,1,2,3~4.Seven days after the onset of stroke,the patients were assessed with the Montreal Cognitive Assessment Scale (MoCA).The patients were divided into cognitive impairment group and non-cognitive impairment group.A total of 168 patients completed the assessment.Results Age,hypertension,smoking history,MOCA score,CHA2DS2-VASC score are related to total CSVD score.Cognitive impairment after atrial fibrillation-related stroke is related to total CSVD score,age,smoking history,drinking history,CHA2DS2-VASc score,frontal lobe and thalamic infarction.Cognitive domain impairment is mainly visual space,executive ability,linguistic ability and delayed recall ability.Conclusion The severity of the overall burden of CSVD is related to cognitive impairment in patients with atrial fibrillation-related stroke.
- Full text:2024073013015290740Relationship between total burden of small vessel disease and cognitive impairment in patients with atrial fibrillation related stroke.pdf