A Fatal Case of Naegleria fowleri Meningoencephalitis in Taiwan.
10.3347/kjp.2013.51.2.203
- Author:
Mei Yu SU
1
;
Ming Shih LEE
;
Ling Yuh SHYU
;
Wei Chen LIN
;
Pei Ching HSIAO
;
Chi Ping WANG
;
Dar Der JI
;
Ke Min CHEN
;
Shih Chan LAI
Author Information
1. Clinical Laboratory, Chung Shan Medical University Hospital, Taichung, Taiwan.
- Publication Type:Case Reports
- Keywords:
Naegleria fowleri;
meningoencephalitis;
fatal case;
amphotericin B;
Taiwan
- MeSH:
Aged;
Amebiasis/*diagnosis/parasitology/*pathology;
Central Nervous System Protozoal Infections/*diagnosis/parasitology/*pathology;
Cerebrospinal Fluid/parasitology;
DNA, Protozoan/chemistry/genetics;
Fatal Outcome;
Humans;
Male;
Microscopy;
Naegleria fowleri/classification/genetics/*isolation & purification;
Polymerase Chain Reaction;
Sequence Analysis, DNA;
Taiwan
- From:The Korean Journal of Parasitology
2013;51(2):203-206
- CountryRepublic of Korea
- Language:English
-
Abstract:
After bathing at a hot spring resort, a 75-year-old man presented to the emergency department because of seizure-like attack with loss of conscious. This is the first case of primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri in Taiwan. PAM was diagnosed based on detection of actively motile trophozoites in cerebrospinal fluid using a wet-mount smear and the Liu's stain. The amoebae were further confirmed by PCR and gene sequencing. In spite of administering amphotericin B treatment, the patient died 25 days later.
