Recognition of whole blood transfusion in civilian trauma resuscitation

VernacularTitle:低效价O型全血在国外创伤救治中的应用进展
Author: Weijuan MA ¹ ; Shaomin REN ; Zhongsi YANG ; Yanhua ZHANG
Author Information

1. 青岛市中心血站,山东青岛 266071
Keywords: whole blood(WB); low titer group O whole blood(LTOWB); blood component transfusion(BCT); mas-sive transfusion protocol(MTP); damage control resuscitation(DCR)
From: Chinese Journal of Blood Transfusion 2024;37(5):602-606
CountryChina
Language:Chinese
Abstract: There has been a growing amount of evidence that a balanced blood component transfusion with roughly equal ratio of units of packed red blood cells,fresh frozen plasma,and platelets leads to better outcomes in massive transfusion re-suscitation of trauma victims.Therefore,the great interest of massive transfusion protocol(MTP)with whole blood was a-roused.Low titer group O whole blood(LTOWB)is implemented in routine use for civilian prehospital ambulance services in large trauma centers of most European and American countries nowadays.There is a growing body of evidence to date to support that early use of LTOWB in patients with life-threatening bleeding improve their survival.In view of the current situ-ation of whole blood supply in our country,most trauma resuscitation guidelines still recommend balanced component trans-fusion for MTPs in the early stage of resuscitation.The research and application of LTOWB abroad will be introduced in this article.