Recognition of whole blood transfusion in civilian trauma resuscitation

VernacularTitle:低效价O型全血在国外创伤救治中的应用进展
Author: Weijuan MA ¹ ; Shaomin REN ¹ ; Zhongsi YANG ¹ ; Yanhua ZHANG ¹
Author Information

1. Qingdao Blood Center, Qingdao 266071, China
Publication Type:Journal Article
Keywords: whole blood(WB); low titer group O whole blood(LTOWB); blood component transfusion(BCT); massive transfusion protocol(MTP); damage control resuscitation(DCR)
From: Chinese Journal of Blood Transfusion 2024;37(5):602-606
CountryChina
Language:Chinese
Abstract: There has been a growing amount of evidence that a balanced blood component transfusion with roughly equal ratio of units of packed red blood cells, fresh frozen plasma, and platelets leads to better outcomes in massive transfusion resuscitation of trauma victims. Therefore, the great interest of massive transfusion protocol (MTP) with whole blood was aroused. Low titer group O whole blood (LTOWB) is implemented in routine use for civilian prehospital ambulance services in large trauma centers of most European and American countries nowadays. There is a growing body of evidence to date to support that early use of LTOWB in patients with life-threatening bleeding improve their survival. In view of the current situation of whole blood supply in our country, most trauma resuscitation guidelines still recommend balanced component transfusion for MTPs in the early stage of resuscitation. The research and application of LTOWB abroad will be introduced in this article.