Changes in related parameters after secondary preparation of blood components
10.13303/j.cjbt.issn.1004-549x.2024.05.016
- VernacularTitle:血液成分二次制备后相关参数变化
- Author:
Min GUO
1
;
Jun CHEN
;
Ning YANG
;
Miao HE
;
Jianmin LI
;
Wenjuan YANG
Author Information
1. 河北省血液中心,河北 石家庄 050071
- Keywords:
blood components;
primary preparation of blood components;
secondary preparation of blood components;
red blood cells in additive solution leukocytes reduced;
plasma;
washed red blood cells
- From:
Chinese Journal of Blood Transfusion
2024;37(5):586-590,612
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes in related parameters after secondary preparation of blood components,in order to further improve the quality of blood components.Methods Different centrifugation conditions were selected for the preparation of primary blood component red blood cells in additive solution leukocytes reduced,and the quality was tested.Then,using the red blood cells in additive solution leukocytes reduced as the initial blood for secondary preparation,and the red blood cells were washed through the Haemonetics ACP 215 device,and the quality was tested.The preparation pa-rameters of blood components were observed,compared and optimized.Results Under comparable centrifugation effects of different centrifugation conditions,the quality control items,which of primary blood components of red blood cells in additive solution leukocytes reduced and frozen plasma prepared by the separation,such as volume,hemoglobin,hematocrit and re-sidual white blood cells met the relevant national standards.And the quality control items of secondary blood components of washed red blood cells such as the hemoglobin and superalbumin content both met the relevant national standards,while vol-ume exceeded the standard by 7-14 mL,which can be operated to the standard range.In addition,the recovery rate of red blood cells and the clearance rate of plasma protein could reach 75%and 99%respectively.Conclusion There is a certain correlation between primary and secondary preparation of blood components,but the relevant parameters of secondary prepa-ration of blood components can be flexibly adjusted according to the actual situation to ensure that the quality of prepared blood component products meet the national standards,thus ensuring clinical treatment effect and safety.
