IgA deficiency allergic transfusion reaction and its prevention and treatment strategies
10.13303/j.cjbt.issn.1004-549x.2024.06.017
- VernacularTitle:IgA缺乏型过敏性输血反应及防治策略
- Author:
Qiuhong MO
1
;
Xuejun LIU
;
Yi LIU
;
Xian LI
Author Information
1. 南宁中心血站 南宁输血医学研究所,广西 南宁 530003
- Keywords:
IgA deficiency;
allergic transfusion reactions;
anti-IgA;
prevention and treatment
- From:
Chinese Journal of Blood Transfusion
2024;37(6):705-709
- CountryChina
- Language:Chinese
-
Abstract:
IgA deficiency allergic transfusion reaction often occurs in patients with anti-IgA.When blood products con-taining IgA are transfused into these patients,it may lead to severe allergic transfusion reactions,which can be fatal in se-vere cases.This review summarizes the clinical manifestations and influencing factors of immunoglobulin A deficiency(IgAD),as well as the pathogenesis,laboratory test and prevention strategies of allergic transfusion reactions caused by IgA deficiency,so as to enhance prevention awareness of IgA deficiency allergic transfusion reaction in medical staff.