IgA deficiency allergic transfusion reaction and its prevention and treatment strategies
10.13303/j.cjbt.issn.1004-549x.2024.06.017
- VernacularTitle:IgA缺乏型过敏性输血反应及防治策略
- Author:
Qiuhong MO
1
;
Xuejun LIU
1
;
Yi LIU
1
;
Xian LI
1
Author Information
1. Nanning Blood Center, Nanning Institute of Transfusion Medicine, Nanning 530003, China
- Publication Type:Journal Article
- Keywords:
IgA deficiency;
allergic transfusion reactions;
anti-IgA;
prevention and treatment
- From:
Chinese Journal of Blood Transfusion
2024;37(6):705-709
- CountryChina
- Language:Chinese
-
Abstract:
IgA deficiency allergic transfusion reaction often occurs in patients with anti-IgA. When blood products containing IgA are transfused into these patients, it may lead to severe allergic transfusion reactions, which can be fatal in severe cases. This review summarizes the clinical manifestations and influencing factors of immunoglobulin A deficiency (IgAD), as well as the pathogenesis, laboratory test and prevention strategies of allergic transfusion reactions caused by IgA deficiency, so as to enhance prevention awareness of IgA deficiency allergic transfusion reaction in medical staff.
