Clinical features of serotonin syndrome in China:a retrospective analysis of 41 case reports
10.19845/j.cnki.zfysjjbzz.2021.0140
- VernacularTitle:国内41例5-羟色胺综合征文献报告回顾性分析研究
- Author:
Jun WU
1
;
Changsen YIN
1
;
Qiqiang TANG
1
Author Information
1. Department of Geriatrics,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230001,China
- Publication Type:Journal Article
- Keywords:
Serotonin syndrome;
SS;
Literature analysis;
Pathogenesis;
Clinical features
- From:
Journal of Apoplexy and Nervous Diseases
2021;38(6):526-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features,diagnosis and treatment status of serotonin syndrome (SS) in China by analyzing the case report of serotonin syndrome.Methods We studied all case report of serotonin syndrome by database retrieval.The clinical features,treatment and outcome were analyzed statistically.Results A total of 41 patients with serotonin syndrome were collected,the most common clinical features were the increase of blood pressure or heart rate (97.6%),sweating (92.7%),tremor (80.5%),Secondly were myoclonus or myotonia (73.2%),fever (58.6%),agitation or delirium (61%),and disturbance of consciousness (58.5%).Conclusion Selective 5-hydroxytryptamine reuptake inhibitors are still the most common drugs leading to serotonin syndrome.The most common features were autonomic nervous system disorders,followed by neuromuscular symptoms,mental or consciousness changes.At present,the prevention and diagnosis of serotonin syndrome have not been given enough attention in our country.Early detection and early intervention have a positive effect on reducing the clinical adverse outcome.
- Full text:2024072922124294379Clinical features of serotonin syndrome in China_a retrospective analysis of 41 case reports.pdf
