Correlation between serum uric acid level and acute idiopathic inflammatory demyelinating disease
- VernacularTitle:血清尿酸水平与急性特发性炎性脱髓鞘疾病的相关性研究
- Author:
Fei YU
1
;
Xiao ZHANG
1
;
Xiaohang ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Multiple sclerosis; Neuromyelitis optica; Uric acid
- From: Journal of Apoplexy and Nervous Diseases 2021;38(7):629-632
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the correlation between serum UA expression levels and disease activity in patients with idiopathic inflammatory demyelinating disease.Methods To test serum UA level of the observation group（40 MS patients in observation group，27 NMO patients in observation group） and 67 controls，compare the difference of UA expression between observation group and control group；The relationship between serum UA level and sex，age of onset and EDSS score was also analyzed.Results（1） The serum UA expression levels in the MS and NMO group was lower than that in the control group；（2）The UA level of male MS patients in the observation group was higher than that of women，all differences were statistically significant（P<0.05）；There was no significant difference in UA between men and women in the observation group（P>0.05）；（3）There was no correlation between UA value，onset age and EDSS score of MS and NMO patients in observation group（P>0.05）.Conclusions The changes of serum UA play an important role in MS and NMO disease activity and pathological injury；Sex has certain influence on the regulation of ua in MS and pathogenesis；The level of serum UA in MS and NMO patients was not related to age and EDSS score.
- Full text:2024072921385606259Correlation between serum uric acid level and acute idiopathic inflammatory demyelinating disease.pdf
