Risk factors of stroke-associated pneumonia in patients with acute ischemic stroke treated with intravenous thrombolysis
10.19845/j.cnki.zfysjjbzz.2021.0184
- VernacularTitle:急性缺血性脑卒中静脉溶栓患者并发卒中相关性肺炎的危险因素分析
- Author:
Yuming KONG
1
;
Zhizhang LI
1
;
Yunhua YUE
1
Author Information
1. Department of Neurology，Yangpu Hospital Tongji University School of Medicine,Shanghai 200090,China
- Publication Type:Journal Article
- Keywords:
Acute ischemic stroke;
Intravenous thrombolysis;
Stroke-associated pneumonia;
Risk factors
- From:
Journal of Apoplexy and Nervous Diseases
2021;38(8):693-695
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of stroke-associated pneumonia (SAP) in patients with acute ischemic stroke (AIS) treated with intravenous thrombolysis.Methods A total of 798 patients with AIS who received intravenous thrombolysis therapy with alteplase from the Department of Neurology,Yangpu Hospital,Tongji University from January 2016 to December 2020 were retrospectively selected and divided into pneumonia group and non-pneumonia group according to the presence or the absence of SAP.The clinical of the two groups were compared.Multivariate logistic regression analysis was used to analyze the independent risk factors of SAP.Results Of 798 cases,115 cases occurred SAP.By multivariate logistic regression analysis,age≥70 years(OR=2.846,95%CI 2.311~5.083,P<0.001),diabetes(OR=2.291,95%CI 1.601~3.945,P=0.003),chronic obstructive disease(OR=2.064,95%CI 1.759~3.528,P=0.005),NIHSS score at admission>8(OR=1.814,95%CI 1.502~2.452,P<0.001),unconsciousness(OR=2.325,95%CI 2.005~3.404,P=0.008),dysphagia(OR=2.457,95%CI 2.221~4.017,P<0.001),hemorrhagic transformation(OR=1.828,95%CI 1.653~2.523,P=0.012) were independent risk factors of SAP in AIS patients treated with intravenous thrombolysis.Conclusion Age≥70 years,diabetes,chronic pulmonary disease,NIHSS score at admission,unconsciousness,dysphagia,hemorrhagic transformation were independent risk factors of SAP in AIS patients treated with thrombolysis.
- Full text:2024072919372337094Risk factors of stroke-associated pneumonia in patients with acute ischemic stroke treated with intravenous thrombolysis.pdf
