25-Hydroxyvitamin D and C-reactive protein levels in Patients with Vestibular Neuritis
- VernacularTitle: 前庭神经炎患者25羟维生素D和C反应蛋白水平的研究
- Author:
Xiuhua LI
1
;
Meng MENG
1
;
Jiangman SONG
1
Author Information
- Publication Type:Journal Article
- Keywords: Vestibular neuritis ； C-reactive protein ； 25-Hydroxyvitamin D
- From: Journal of Apoplexy and Nervous Diseases 2021;38(9):829-832
- CountryChina
- Language:Chinese
- Abstract: Objective We evaluated serum levels of 25hydroxyvitamin D（25（OH）D）and Creactive protein（CRP）in patients presenting acutely with Vestibular neuritis（VN）and healthy controls and investigated the possible correlation of serum 25（OH）D and CRP levels with VN.Methods A total of 46 consecutive patients diagnosed with VN within 7 days of symptom onset and 66 ageand sexmatched healthy controls in NO731 Hospital，between March 2019 and August 2020 were recruited. Demographic and clinical data，such as age，sex，height，weight，living habits，ongoing health problems，and medication history，for all subjects were recorded，and levels of 25（OH）D and CRP were measured and compared. 〖WT5”HZ〗Results〖WT5”BZ〗Serum levels of 25（OH）D were significantly lower in patients with VN than in controls（18.30± 6.19 vs. 22.43±5.23 ng/ml，P<0.001）.whereas serum levels of CRP were higher in patients with VN than in controls （15.86±8.37 vs. ng/ml，P<0.001）Regression analyses demonstrated that vitamin D and CRP were associated with VN，with an odds ratio of 1.187 （95%CI 1.046～1.093，P=0.001）and 1.223 （95%CI=1.10～1.36，P=0.000）.Conclusion VN is associated with evidence of an acute inflammatory response，we found that serum 25（OH）D and CRP may be associated with VN occurrence.
- Full text:202407291054369257525-Hydroxyvitamin D and Creactive protein levels in Patients with Vestibular Neuritis.pdf
