Correlation between red blood cell distribution width and post-stroke depression
- VernacularTitle: 红细胞分布宽度与急性缺血性卒中后抑郁的相关性研究
- Author:
Li MU
1
;
Yaqiang LI
1
;
Xianping ZHOU
1
Author Information
- Publication Type:Journal Article
- Keywords: Stroke; Post-stroke depression; Red blood cell distribution width; Depression
- From: Journal of Apoplexy and Nervous Diseases 2021;38(11):1012-1016
- CountryChina
- Language:Chinese
- Abstract: To investigate the relationship between red blood cell distribution width （RDW） and poststroke depression in patients with acute ischemic stroke. Methods Continuous collection of patients with acute cerebral infarction admitted to our hospital from May 2017 to May 2020.All cases were divided into the non PSD group and PSD group according to whether they were diagnosed with depression at 3 months. The clinical data of the patients were recorded，and RDW was detected by automatic five-classification blood cell analyzer in the morning of the second day after admission. Multivariate Logistic regression analysis were used to screen the risk factors of PSD.The ROC curve analysis was performed to evaluate the predictive value. Results A total of 413 eligible patients were included，with an average age of 65.89 years（aged 40 to 86 years） and 169 males （40.92%）.During the follow-up 3 months after onset，the total number of patients diagnosed with depression was 88例（21.31%）.Multivariate Logistic regression analysis showed that the admission NIHISS score（OR=1.134，95%CI1.049～1.225，P<0.001）and infarction of key areas（OR=1.363，95%CI 1.205～1.641，P<0.001），Female（OR=1.888，95%CI1.097～3.249，P=0.022）RDW（OR=3.730，95%CI 2.229～6.051，P<0.001）were independent risk factors for PSD. The area under the ROC curve （AUC） of RDW for predicting poor prognosis was 0.709（95%CI 0.656～0.763，P<0.001），the optimal cut-off value was 13.01%，the sensitivity was 77.6% and the specificity was 55.7%.Conclusion RDW was an independent risk factor for post stroke depression at 3 months in acute ischemic stroke patients.
- Full text:2024072822582815943Correlation between red blood cell distribution width and poststroke depression.pdf
