Clinical analysis of lakosamine in the treatment of 44 cases of focal epilepsy
- VernacularTitle:拉考沙胺治疗44例局灶性癫痫的疗效分析
- Author:
Jing GAO
1
;
Jie REN
1
;
Aixian LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Lakosamine; Focal epilepsy; Clinical analysis; Attack frequency
- From: Journal of Apoplexy and Nervous Diseases 2021;38(12):1092-1094
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the clinical efficacy and tolerance of lakosamine in the treatment of patients with focal epilepsy.Methods Forty-four cases of focal epilepsy patients who received LCM from from March 2019 to July 2020 department of neurology,Kunming san bo hospital and the first affiliated hospital of Kunming medical university.The seizures and tolerance of the forty-four patients were followed up in February 2021.Results After the addition of LCM drugs,the frequency of epileptic seizures in patients with follow-up time of at least 6 months was significantly reduced,the difference was statistically significant (P<0.01).The efficiency can be up to 81.81% and Retention rates can reach 83%.Conclusions As the third generation of new Anti-seizure medications,LCM can effectively reduce the frequency of epileptic seizures in some patients with focal epilepsy.Very few patients had intolerable adverse reactions.
- Full text:2024072822103837439Clinical analysis of lakosamine in the treatment of 44 cases of focal epilepsy.pdf
