The clinical value of variation coefficient and standard deviation of erythrocyte distribution width in diagnosis of colorectal cancer metastasis
10.19405/j.cnki.issn1000-1492.2023.04.030
- Author:
Shuomin Wang
1
;
Yong Zhu
2
;
Yunhong Xia
1
Author Information
1. Dept of Oncology，The First Affiliated Hospital of Anhui Medical University，Hefei 230012 ;Dept of Oncology，Anhui Public Health Clinical Center，Hefei 230012
2. Dept of Oncology，The First Affiliated Hospital of Anhui Medical University，Hefei 230012 ;Dept of General Surgery，Anhui Public Health Clinical Center，Hefei 230012
- Publication Type:Journal Article
- Keywords:
colorectal cancer;
metastasis;
coefficient of variation of erythrocyte distribution width;
standard devia- tion of erythrocyte distribution width
- From:
Acta Universitatis Medicinalis Anhui
2023;58(4):698-701
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of coefficient of variation ( RDW-CV) and standard deviation (RDW-SD) of erythrocyte distribution width in the diagnosis of colorectal cancer ( CRC) metastasis．
Methods :91 CRC inpatients were selected as the research subjects．According to whether the tumor was metastatic，they were divided into two groups : 61 cases in the non-metastatic group and 30 cases in the metastasis group．The laboratory indicators of the two groups of patients included : neutrophils count，lymphocyte count，platelet count，carcinoembryonic antigen，plasma prothrombin time，activated partial thromboplastin time，fibrinogen，thrombin time， RDW-CV and RDW-SD and other indicators．The t test was used to compare the means of the two groups，and the pearson correlation was used to analyze the relationship between RDW-CV and RDW-SD with neutrophil count， lymphocyte count，neutrophil count-lymphocyte count ratio (NLR) and carcinoembryonic antigen．Correlation coefficient，receiver operating characteristic curve ( ROC) to assess the area under the curve ( AUC) of RDW-CV， RDW-SD，carcinoembryonic antigen and their combined diagnosis in assessing CRC metastasis.
Results:Compared with non-metastatic patients，the RDW-CV and RDW-SD values of metastatic patients were higher (both P < 0. 05) ．Both RDW-CV and RDW-SD levels were positively correlated with carcinoembryonic antigen content．Compared with the AUC of carcinoembryonic antigen in diagnosis of CRC metastasis，the AUC of RDW-CV or RDW-SD combined with carcinoembryonic antigen was higher．
Conclusion:RDW-CV and RDW-SD have potential clinical application value in differential diagnosis of CRC metastasis.
- Full text:2024072720344039752红细胞分布宽度变异系数及标...直肠癌转移诊断中的临床价值_汪硕敏.pdf
