Clinical significance of transcranial Doppler ultrasonography to evaluate intracranial collateral circulation in patients with extracranial segment of unilateral internal carotid artery occlusion
- VernacularTitle: 经颅多普勒超声评估单侧颈内动脉颅外段闭塞患者颅内侧支循环的临床意义
- Author:
Mengxiao FANG
1
;
Pinjing HUI
1
;
Tong SUN
1
Author Information
- Publication Type:Journal Article
- Keywords: Transcranial Doppler ultrasound; Internal carotid artery; occluded; Collateral circulation; Ischemic stroke
- From: Journal of Apoplexy and Nervous Diseases 2022;39(1):12-17
- CountryChina
- Language:Chinese
- Abstract: To investigate the clinical value of transcranial Doppler ultrasound （TCD） in evaluating intracranial collateral circulation in patients with extracranial segment of unilateral internal carotid artery occlusion （ICAO）. Methods A total of 145 patients with ICAO，109 in the symptomatic group and 36 in the asymptomatic group，who were diagnosed by cervical vascular ultrasonography and confirmed by digital subtraction angiography （DSA） in the Stroke Center of the First Affiliated Hospital of Soochow University from January 2018 to December 2020，were retrospectively enrolled. TCD was recorded to evaluate intracranial collateral circulation types and performed consistency test with DSA.The hemodynamic parameters of bilateral middle cerebral artery （MCA） and CT perfusion （CTP） parameters of bilateral basal ganglia and temporal lobe were recorded. According to the Collateral circulation assessment system of the American Society for Interventional and Therapeutic Neuroradiology/Society for Interventional Radiology （ASITN/SIR），patients were divided into poor collateral circulation（grade 0～2） and good collateral circulation （grade 3～4），and the differences of MCA parameters and CTP parameters were compared between the two groups. The differences in bilateral MCA blood flow parameters between the asymptomatic group and the symptomatic group and the early CT scores （ASPECTS） of the Alberta Stroke Project were compared.Results （1） Consistency analysis：The coincidence rates of anterior communicating artery （ACoA），posterior communicating artery （PCoA），ocular artery （OA） and DSA evaluated by TCD were：93.1%，91.0%，80.7%，with good consistency （Kappa value=0.84，0.78，0.66，all P<0.05）.（2）Collateral circulation compensation：The mean flow rate（Vm），peak systolic flow rate （Vs），end diastolic flow rate （Vd） and pulsation index （PI）of the affected middle cerebral artery in the poor collateral circulation group were lower than those in the good group，and the differences in Vm，Vs and Vd were statistically significant （P<0.05）. CBF and CBV in basal ganglia and temporal lobe were decreased，while MTT and TTP were prolonged，with statistically significant differences（all P<0.05）.（3）ASPECTS in asymptomatic group were significantly higher than those in symptomatic group，and blood flow parameters in MCA of healthy side were less different than those in symptomatic group （all P<0.01）.Conclusion TCD is consistent with DSA in evaluating intracranial collateral circulation in patients with intracranial extracranial occlusion of unilateral internal carotid artery.MCA blood flow parameters can reflect the perfusion in the blood supply area，and TCD is an effective tool for evaluating intracranial collateral circulation.
- Full text:2024072710211578738Clinical significance of transcranial Doppler ultrasonography to evaluate intracranial collateral circulation in patients with extracranial segment of unilateral internal carotid artery occlusion.pdf
