Predictive value of pre-treatment liver function indexes on the clinical severity at nadir and prognosis of patients with Guillain-Barré Syndrome
- VernacularTitle:治疗前肝功能指标对吉兰-巴雷综合征患者疾病严重程度及预后的预测价值
- Author:
Baojun QIAO
1
;
Min WANG
1
;
Shuhu ZHOU
1
Author Information
- Publication Type:Journal Article
- Keywords: Guillain-Barré Syndrome; Liver function indexes; Clinical severity; Prognosis
- From: Journal of Apoplexy and Nervous Diseases 2022;39(3):251-254
- CountryChina
- Language:Chinese
- Abstract: To explore the predictive value of liver function indexes on the clinical severity at nadir and prognosis of patients with Guillain-Barré Syndrome（GBS）. Methods The clinical data of 206 GBS patients hospitalized in the affiliated hospital of Jining Medical University from January 2010 to September 2016 were analyzed retrospectively. Multivariate logistic regression analysis was used to analyze the independent factors affecting the severity and prognosis of GBS patients. The receiver operator characteristic curve （ROC） was used to evaluate the predictive value of pretreatment liver function indexes on the severity at nadir and prognosis of GBS patients. Results Albumin，A/G ratio，GGT，and ball palsy were the risk factors that affected the severity of disease in GBS patients at the peak （all P<0.05）；albumin，GGT，and mechanical ventilation were the risk factors for prognosis of GBS patients （all P values<0.05）. Conclusion Albumin and GGT have potentials to predict clinical severity at nadir and outcome at 6 months in patients with GBS.
- Full text:2024072610333382352Predictive value of pretreatment liver function indexes on the clinical severity at nadir and prognosis of patients with GuillainBarré Syndrome.pdf
