Relationship between GNRI and perioperative rehabilitation of elderly patients with gastric cancer
10.19405/j.cnki.issn1000-1492.2022.11.023
- Author:
Hanhan Wu
1
;
Jianhua Jiang
1
;
Jing Cheng
1
;
Yunshan Fan
1
;
Lili Hou
1
;
Shixia Guan
1
;
Le Yang
1
;
Shuang Zu
1
;
Huixian Li
1
;
Bao Zhang
1
;
Anla Hu
2
Author Information
1. Dept of Endocrinology，Dept of Clinical Nutriology，The First Affiliated Hospital of Anhui Medical University，Hefei 230022
2. Dept of Nutrition and Food Hygiene， School of Public Health，Anhui Medical University，Hefei 230032
- Publication Type:Journal Article
- Keywords:
gastric cancer;
GNRI;
perioperative period;
nutritional status;
complications
- From:
Acta Universitatis Medicinalis Anhui
2022;57(11):1816-1820
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore the relationship between geriatric nutritional risk index( GNRI) and perioperative nutritional status，postoperative recovery and complications in elderly patients with gastric cancer．
Methods :In this retrospective study，212 elderly patients ( aged ≥60 years ) with gastric cancer who underwent gastrectomy were recruited．GNRI was used to retrospectively assess the patients' preoperative nutritional status ，and analyze the relationship between GNRI and perioperative nutritional status，postoperative recovery and complications．The ROC curve was applied to explore the value of GNRI in predicting postoperative complications.
Results :The inci- dence of preoperative nutritional risk in elderly patients undergoing gastric cancer surgery was 45. 07%．Compared with the patients whose GNRI＞98 points，the patients whose GNRI≤98 points had different degrees of decrease in serum total protein，albumin，prealbumin，hemoglobin and lymphocyte counts before surgery，day 1 and day 5－8 after surgery (P ＜0. 05) ．The patients whose GNRI ＜92 points had longer postoperative hospital stay than those with GNRI＞98 points (P＜0. 05) ．With the decrease of GNRI scores，the incidence of complications showed an upward trend(P＜0. 001) ．The multivariate analysis of the relationship between GNRI and postoperative complica- tions showed that TNM staging of III －IV and GNRI ＜92 points were independent risk factors for complications. GNRI had a good predictive value for the occurrence of complications (AUC = 0. 639，95% CI : 0. 570－0. 703，P = 0. 001，Cut-off value : 92. 21) ．
Conclusion :GNRI can be used for preoperative nutritional assessment for eld- erly gastric cancer patients．Patients with GNRI＜92. 21 points should be actively given nutritional therapy to im- prove perioperative nutritional status，speed up postoperative recovery，and reduce the occurrence of complications.
- Full text:2024072521474087270老年营养风险指数与老年胃癌患者围手术期康复的关系_吴寒寒.pdf
