The clinical value of Neutrophil to lymphocyte ratio in differentiating multiple sclerosis and neuromyelitis optica spectrum disorders
10.19845/j.cnki.zfysjjbzz.2022.0079
- VernacularTitle:中性粒细胞/淋巴细胞比值在多发性硬化和视神经脊髓炎谱系疾病中的鉴别诊断价值
- Author:
Zhenghao DUAN
1
;
Juan FENG
1
Author Information
1. Department of Neurology,Shengjing Hospital of China Medical University,Shenyang 110004,China
- Publication Type:Journal Article
- Keywords:
Multiple sclerosis ； Neuromyelitis optica spectrum disorders；Neutrophil to lymphocyte ratio；Differential diagnosis
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(4):310-312
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the difference of Neutrophil to lymphocyte ratio (NLR) among multiple sclerosis (MS),neuromyelitis optica spectrum disorders (NMOSD),and healthy people,and analyze the clinical value in differentiating MS and NMOSD.Method Clinical data and laboratory results from patients admitted to Shengjing hospital who were diagnosed with MS or NMOSD,and calculate NLR were retrospectively analyzed.Fifty healthy people matched with sex and age were selected as controls.Result There were significant differences of neutrophils,lymphocyte,monocyte and NLR among MS,NMOSD and healthy people.The area under curve of ROC in differentiating MS and NMOSD was 0.796 (P<0.001,95%CI 0.685~0.907).Conclusion The NLR of patients with MS was higher than healthy control,but lower than NMOSD.And NLR was a helpful marker to differentiate MS and NMOSD.
- Full text:2024072520553888829The clinical value of Neutrophil to lymphocyte ratio in differentiating multiple sclerosis and neuromyelitis optica spectrum disorders.pdf
