Changes of mean corpuscular volume in patients with cerebral infarction with negative diffusion-weighted imaging
10.19845/j.cnki.zfysjjbzz.2022.0181
- VernacularTitle:弥散加权成像阴性脑梗死患者平均红细胞体积变化特征
- Author:
Aiyong YU
1
;
Liang TANG
1
Author Information
1. Department of Neurology,Shanghai Songjiang District Central Hospital,Shanghai 201699,China
- Publication Type:Journal Article
- Keywords:
Diffusion-weighted imaging;
Cerebral infarction;
Mean red blood cell volume;
Pathogenesis
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(8):723-726
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of changes in mean red blood cell volume in patients with DWI-negative cerebral infarction.Methods The patients were divided into two groups:(1)DWI negative group:46 patients.(2)DWI positive group:59 patients.All patients underwent routine axial,coronal,and sagittal thin-section DWI examinations on a 3.0T MRI scanner.The general information of the patients was recorded,and the electrolyte levels,carbon dioxide binding capacity,blood lipids,renal function and coagulation function of the patients were determined.Plasma osmotic pressure was calculated.The patient’s white blood cells,red blood cells,platelets,hemoglobin,mean corpuscular volume (MCV),hematocrit,mean platelet volume,platelet volume,and mean platelet volume were measured.Results There was no significant difference in plasma osmotic pressure,carbon dioxide binding capacity,blood calcium concentration,hematocrit,mean platelet volume,platelet volume and D-dimer level between the DWI-negative group and the DWI-positive group (P values equal to 0.290,0.558,0.113,0.090,0.401,0.460,0.510 respectively).Compared with the DWI-positive group,the mean corpuscular volume of the DWI-negative group increased (P=0.009).Logistic regression analysis showed that the increase in mean red blood cell volume was an independent factor for DWI-negative cerebral infarction (OR=2.864,95%CI 1.385~5.360,P=0.003).Conclusion Patients with negative imaging on DWI sequences are characterized by increased mean corpuscular volume in the blood.
- Full text:2024072322531102079Changes of mean corpuscular volume in patients with cerebral infarction with negative diffusion-weighted imaging.pdf