Predictive model for early neurological deterioration in minor ischemic stroke without reperfusion therapy
10.19845/j.cnki.zfysjjbzz.2022.0179
- VernacularTitle:非再灌注的轻型卒中早期神经功能恶化预测
- Author:
Yuchan LIANG
1
;
Xiaoyan HAN
1
;
Sujuan LI
1
Author Information
1. Department of Neurology,Zhaoqing First People Hospital,Zhaoqing 526000,China
- Publication Type:Journal Article
- Keywords:
Acute ischemic stroke;
Minor stroke;
Non-reperfusion;
Cerebral atherosclerosis score
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(8):713-718
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore independent risk factors for early neurological deterioration in first-ever minor ischemic stroke without reperfusion therapy,and to achieve individualized prediction by constructing a nomogram model.Methods We enrolled first-ever minor ischemic stroke patients of non-reperfusion therapy from January 1,2017 to December 31,2019 in the Zhaoqing First People’s Hospital.The clinical and imaging data of the Neurological deterioration group(END group) and the non-END group were analyzed.The independent related factors were screened and the nomogram model was constructed.Results A total of 384 cases were enrolled,including 66 cases (17.19%) in the END group and 318 cases (82.81%) in the non-END group.Logistic regression analysis showed that diabetes mellitus,TOAST typing,albumin levels,and cerebral atherosclerosis score (CAS) were independent influencing factors (P<0.05).The nomogram model is constructed and the ROC curve is generated,and the area under the curve is 0.859［95%CI(0.758,0.864)］.Model consistency can be hinted at by the calibration curve and the Hoster-Lemeshow test.Finally,the clinical decision curve indicates that the model has clinical application value.Conclusion This study explores the nomogram model for END in first-ever minor ischemic stroke without reperfusion therapy,which has some clinical application value,is composed of four major factors:diabetes mellitus,TOAST typing,albumin level and CAS.
- Full text:2024072322480342262Predictive model for early neurological deterioration in minor ischemic stroke without reperfusion therapy.pdf
