Association between white blood cell count,absolute and relative neutrophil count and prognosis in young patients with ischemic stroke
10.19845/j.cnki.zfysjjbzz.2022.0172
- VernacularTitle:白细胞计数、中性粒细胞绝对值及相对值与青年卒中患者预后的相关性研究
- Author:
Jiaokun JIA
1
;
Yanfang LIU
1
;
Jiahuan GUO
1
Author Information
1. Department of Neurology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China
- Publication Type:Journal Article
- Keywords:
Ischemic stroke in young;
Prognosis;
White blood cell count;
Absolute neutrophil count;
Relative neutrophil count
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(8):676-680
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study aims to explore the correlation between white blood cell count (WBC),absolute neutrophil count (ANC),relative neutrophil count (RNC) and neurological impairment,poor prognosis at discharge and 90 days after onset.Methods This study was a retrospective study,including patients aged 18 to 45 years old with first ischemic stroke within 72 hours.NIHSS score at discharge,mRS score at discharge and 90 days were used as outcome.Multivariate logistic regression was used to analyze the relationship between WBC quartile,ANC,RNC and neurological deficit (NIHSS score>4) and poor prognosis (mRS score 2~5).Results WBC>7.82×10 9/L was independently associated with moderate and severe neurological deficit at discharge and poor prognosis at 90 days.The ANC was only associated with poor prognosis at 90 days,independently.The RNC was an independent risk factor for moderate and severe neurological impairment at discharge,poor prognosis at discharge and 90 days.Conclusion WBC>7.82×10-9/L is an independent risk factor for moderate and severe neurological impairment at discharge and poor prognosis at 90 days in young patients with stroke.The increase of RNC,which is independently related to moderate and severe neurological impairment and poor prognosis,is more indicative than ANC for poor prognosis in young patients with stroke.
- Full text:202407232226234677Association between white blood cell count,absolute and relative neutrophil count and prognosis in young patients with ischemic stroke.pdf
