The clinical effects of beprost sodium tablets combined with Epley repositioning maneuver in treatment of postrior semicircular canal benign paroxysmal positional vertigo
- VernacularTitle:贝前列素钠联合Epley法治疗后半规管良性阵发性位置性眩晕疗效分析
- Author:
Wei JIA
1
;
Xiaowei LIU
1
;
Zhaochen LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Beprost sodium; Betahistine mesylate; Benign paroxysmal positional vertigo; Manual reduction; Clinical effects
- From: Journal of Apoplexy and Nervous Diseases 2022;39(9):813-817
- CountryChina
- Language:Chinese
- Abstract: To study the clinical effects of beprost sodium tablets combined with Epley manual reduction in treatment of benign paroxysmal positional vertigo（BPPV）. Methods A total of 338 patients with posterior semicircular canal BPPV who were treated in the neurogy clinic of our hospital from January 2019 to December 2020 were enrolled in the study，who were randomly divided into the observation group，who were treated in Epley manual reduction combined with oral beprost sodium tablets，118 cases；control group 1，who were treated with only Epley manual reduction，114 cases and control group 2，who were treated with Epley manual reduction combined with oral betahistine mesilate tablets，106 cases. The clinical efficacy，vestibular symptom index（VSI），dizziness handicap inventory（DHI） and relapse rate were observed and compared between the three groups. Results The total effective rate in the observation group was 91.53%，which was significantly higher than that（73.68） in control group1 and（86.79%） in control group2，the difference was statistically significant（P<0.05）. One week and one month After manual reduction，the vestibular symptom index（VSI） scores and the dizziness handicap inventory（DHI） scores in three group were significantly lower than pretreatment，moreover，the decrease degree in the observation group was more significant than the other two control groups，the difference was statistically significant（P<0.05）. Within 3 months after treatment，the relapse rate in the observation group（18.64%）was lower than that in control group1（34.21%） and in control group2（27.36%），the difference was statistically significant（P<0.05）. Conclusion The clinical effects of beprost sodium tablets combined with Epley manual reduction in treatment of posterior semicircular canal BPPV are superior to those by simple Epley manual reduction and by Epley manual reduction combined with betahistine mesilate.
- Full text:202407232210143240The clinical effects of beprost sodium tablets combined with Epley repositioning maneuver in treatment of postrior semicircular canal benign paroxysmal positional vertigo.pdf
