Predictive value of neutrophil/lymphocyte ratio in 90-day risk of death in patients with cardioembolic stroke
10.19845/j.cnki.zfysjjbzz.2022.0227
- VernacularTitle:中性粒细胞/淋巴细胞比值对心源性脑栓塞患者90 d死亡风险的预测价值
- Author:
Peifei JIA
1
;
Liang SUN
1
;
Lan WU
1
Author Information
1. Department of Neurology,The Second Affiliated Hospital of Baotou Medical College,Baotou 014030,China
- Publication Type:Journal Article
- Keywords:
Neutrophil/lymphocyte ratio;
Cardioembolic stroke;
Death;
Predictive value
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(10):913-915
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of neutrophil/lymphocyte ratio (NLR) on the 90 day mortality risk of patients with cardiogenic cerebral embolism (CE).Methods 245 patients with cardiogenic cerebral embolism were analyzed retrospectively.Demographic data,vascular risk factors,laboratory tests and end point events were collected.The patients were divided into survival group and death group according to whether or not there were end-point events.Multifactor logistic regression was used to analyze the influencing factors of endpoint events,to draw ROC curve,and to evaluate the predictive value of NLR on endpoint events.Results Of the 245 cases included in the analysis,145 survived and 100 died.Compared with the survivors,the age,hyperlipidemia,atrial fibrillation,mRS score,white blood cell count,glutathione aminotransferase and neutrophil score in the death group were significantly higher (P<0.01),and there was no significant difference in gender,hypertension,diabetes,family history,smoking,alcohol consumption,red blood cell count,hemoglobin and other blood indicators between the two groups(P>0.05).Multivariate logistic regression analysis showed that age,atrial fibrillation,hyperlipidemia and NLR were independent risk factors for 90-day death.ROC shows AUC=0.7558.When the optimal cutoff value of NLR was 5.65,the sensitivity was 68.0%,and the specificity was 76.6%.Conclusion The increase of NLR at admission is a high risk factor for 90 day death in patients with cardiogenic cerebral infarction,and it has a good predictive value for 90 day death.
- Full text:2024072320571931262Predictive value of neutrophil_lymphocyte ratio in 90-day risk of death in patients with cardioembolic stroke.pdf